David P. Kay

Discovery of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase as Potential Anticancer Agents

Jean‐Damien Charrier, Steven J. Durrant, Julian M.C. Golec et al. · Journal of Medicinal Chemistry · 2011 · 259 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +15

Synthesis and oral antiallergic activity of carboxylic acids derived from imidazo[2,1-c][1,4]benzoxazines, imidazo[1,2-a]quinolines, imidazo[1,2-a]quinoxalines, imidazo[1,2-a]quinoxalinones, pyrrolo[1,2-a]quinoxalinones, pyrrolo[2,3-a]quinoxalinones, and imidazo[2,1-b]benzothiazoles

I. R. Ager, Alan C. Barnes, G. W. DANSWAN et al. · Journal of Medicinal Chemistry · 1988 · 137 citations

Natural Sciences, Medicinal Chemistry, Pharmacology +12

The discovery of the potent aurora inhibitor MK-0457 (VX-680)

David Bebbington, Hayley Binch, Jean‐Damien Charrier et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 99 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis, Structure−Activity Relationships, and Pharmacokinetic Properties of Dihydroorotate Dehydrogenase Inhibitors:  2-Cyano-3-cyclopropyl-3-hydroxy- <i>N</i>-[3‘-methyl-4‘-(trifluoromethyl)phenyl]propenamide and Related Compounds

Elizabeth Kuo, P. Hambleton, David P. Kay et al. · Journal of Medicinal Chemistry · 1996 · 90 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

CH···O and CH···N Hydrogen Bonds in Ligand Design:  A Novel Quinazolin-4-ylthiazol-2-ylamine Protein Kinase Inhibitor

Albert C. Pierce, Ernst ter Haar, Hayley Binch et al. · Journal of Medicinal Chemistry · 2005 · 79 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15