Albert C. Pierce - Concepedia

Author

Albert C. Pierce

Vertex Pharmaceuticals (United States)

Also Known As

, A. Pierce, A.C. Pierce, ALBERT PIERCE, Albert C. Pierce, Albert Pierce, Bazargan, Mohsen, Yaghmaei E.

Publications

1.2K

Citations

H-Index

Concepts

All Affiliations

Vertex Pharmaceuticals (United States)Yale University

About

Albert C. Pierce is an author at Vertex Pharmaceuticals (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	13	887
2	Business	2	2	124
3	Engineering	2	2	49
4	Health Sciences	1	1	20
5	Law	1	1	34

Albert C. Pierce

Publications

1.1K

Citations

H-Index

Page 1

	Year	Citations
Kinase inhibitors and the case for CH…O hydrogen bonds in protein–ligand binding Albert C. Pierce, Kathryn L. Sandretto, Guy W. Bemis Proteins Structure Function and Bioinformatics Molecular PharmacologyBiochemistryCh…o Hydrogen BondsNatural SciencesMedicine	2002	224
BREED: Generating Novel Inhibitors through Hybridization of Known Ligands. Application to CDK2, P38, and HIV Protease Albert C. Pierce, Govinda Rao, Guy W. Bemis Journal of Medicinal Chemistry Combinatorial ChemistryDrug TargetHiv Protease InhibitorsImmunologyMolecular Biology	2004	183
Docking Study Yields Four Novel Inhibitors of the Protooncogene Pim-1 Kinase Albert C. Pierce, Marc Jacobs, Cameron Stuver-Moody Journal of Medicinal Chemistry	2008	124
The Economic Cycle and the Social Suicide Rate Albert C. Pierce American Sociological Review EconomicsSocioeconomicsSuicideSociologyBusiness	1967	90
Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases Luc J. Farmer, Mark W. Ledeboer, Thomas Hoock, Journal of Medicinal Chemistry ImmunologyImmunologic MechanismJanus Tyrosine KinasesCompound LibraryImmunotherapy	2015	87
CH···O and CH···N Hydrogen Bonds in Ligand Design: A Novel Quinazolin-4-ylthiazol-2-ylamine Protein Kinase Inhibitor Albert C. Pierce, Ernst ter Haar, Hayley Binch, Journal of Medicinal Chemistry Molecular BiologyChemical BiologyN Hydrogen BondsMedicinal ChemistryCh···n Hydrogen Bonds	2005	79
Structure-based design of 3-aryl-6-amino-triazolo[4,3-b]pyridazine inhibitors of Pim-1 kinase Ron Grey, Albert C. Pierce, Guy W. Bemis, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryMedicinal ChemistryPim-1 KinaseMedicineRational Drug Design	2009	58
A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors Tiansheng Wang, Mark W. Ledeboer, John P. Duffy, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryNovel ChemotypeBiochemistryMedicine3,4-Ring Fused 7-Azaindoles	2009	48
Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS) Jon H. Come, Philip N. Collier, James A. Henderson, Journal of Medicinal Chemistry ImmunologyPharmacotherapyPharmaceutical ChemistryPre-clinical PharmacologyNeuroinflammation	2018	46
Janus Kinase 2 Inhibitors. Synthesis and Characterization of a Novel Polycyclic Azaindole Tiansheng Wang, John P. Duffy, Jian Wang, Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryDerivative (Chemistry)BiochemistryMedicine	2009	40

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