Steven J. Durrant

Discovery of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase as Potential Anticancer Agents

Jean‐Damien Charrier, Steven J. Durrant, Julian M.C. Golec et al. · Journal of Medicinal Chemistry · 2011 · 256 citations · Full text

Chemoprevention Strategy, Molecular Biology, Molecular Pharmacology +19

Catalyst‐Switchable Regiocontrol in the Direct Arylation of Remote CH Groups in Pyrazolo[1,5‐<i>a</i>]pyrimidines

Robin B. Bedford, Steven J. Durrant, Michelle Montgomery · Angewandte Chemie International Edition · 2015 · 77 citations · Full text

Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors

Jean‐Damien Charrier, Andrew T. Miller, David P. Kay et al. · Journal of Medicinal Chemistry · 2011 · 60 citations · Full text

Kinase Active Site, Medicinal Chemistry, Drug Target +14

Rational Design of 5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine (VX-970, M6620): Optimization of Intra- and Intermolecular Polar Interactions of a New Ataxia Telangiectasia Mutated and Rad3-Related (ATR) Kinase Inhibitor

Ronald M. A. Knegtel, Jean‐Damien Charrier, Steven J. Durrant et al. · Journal of Medicinal Chemistry · 2019 · 53 citations · Full text

Catalyst‐Switchable Regiocontrol in the Direct Arylation of Remote CH Groups in Pyrazolo[1,5‐<i>a</i>]pyrimidines

Robin B. Bedford, Steven J. Durrant, Michelle Montgomery · Angewandte Chemie · 2015 · 15 citations · Full text