Steven J. Durrant

Discovery of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase as Potential Anticancer Agents

Jean‐Damien Charrier, Steven J. Durrant, Julian M.C. Golec et al. · Journal of Medicinal Chemistry · 2011 · 259 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +15

Catalyst‐Switchable Regiocontrol in the Direct Arylation of Remote CH Groups in Pyrazolo[1,5‐<i>a</i>]pyrimidines

Robin B. Bedford, Steven J. Durrant, Michelle Montgomery · Angewandte Chemie International Edition · 2015 · 79 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +17

Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors

Jean‐Damien Charrier, Andrew T. Miller, David P. Kay et al. · Journal of Medicinal Chemistry · 2011 · 61 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Rational Design of 5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine (VX-970, M6620): Optimization of Intra- and Intermolecular Polar Interactions of a New Ataxia Telangiectasia Mutated and Rad3-Related (ATR) Kinase Inhibitor

Ronald M. A. Knegtel, Jean‐Damien Charrier, Steven J. Durrant et al. · Journal of Medicinal Chemistry · 2019 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Catalyst‐Switchable Regiocontrol in the Direct Arylation of Remote CH Groups in Pyrazolo[1,5‐<i>a</i>]pyrimidines

Robin B. Bedford, Steven J. Durrant, Michelle Montgomery · Angewandte Chemie · 2015 · 15 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +17