Vertex Pharmaceuticals (United Kingdom)

Super-diversity and its implications

Steven Vertovec · Ethnic and Racial Studies · 2007 · 5.3K citations

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore et al. · Nature Medicine · 2004 · 948 citations · Full text

Selective Small-molecule Inhibitor, Signal Transduction, Signaling Pathway +11

Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR

Philip M. Reaper, Matthew R. Griffiths, Joanna Long et al. · Nature Chemical Biology · 2011 · 631 citations

Tumor Biology, P53-deficient Cancer Cells, Selective Killing +9

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

Chris T. Williamson, Rowan Miller, Helen N. Pemberton et al. · Nature Communications · 2016 · 375 citations · Full text

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation

Emmanouil Fokas, Remko Prevo, John R. Pollard et al. · Cell Death and Disease · 2012 · 353 citations · Full text