Concepedia

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore, Richele K. Rasmussen, Abi O Ajose-Adeogun, Tomoko Nakayama, Joanne A Graham, Cécile Demur, Thierry Hercend, Anita Diu‐Hercend,

Nature Medicine · 2004 · 954 citations · 37 references

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37

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

James R. Bischoff · The EMBO Journal · 1998 · 1.2K citations · Full text

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Claire Ditchfield, Victoria Johnson, Anthony Tighe et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

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Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes

Jer-Yuan Hsu, Zu-Wen Sun, Xiu-Min Li et al. · Cell · 2000 · 863 citations

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Mitotic Phosphorylation of Histone H3: Spatio-Temporal Regulation by Mammalian Aurora Kinases

Claudia Crosio, Gian María Fimia, Romain Loury et al. · Molecular and Cellular Biology · 2002 · 665 citations · Full text

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Aurora-A and an Interacting Activator, the LIM Protein Ajuba, Are Required for Mitotic Commitment in Human Cells

Toru Hirota, Naoko Kunitoku, Takashi Sasayama et al. · Cell · 2003 · 622 citations · Full text

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