Zainab M. Doctor

Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation

Baishan Jiang, Michael A. Erb, Yanke Liang et al. · Nature Chemical Biology · 2017 · 531 citations · Full text

Selective Cdk9 Inhibition, Medicine, Receptor Tyrosine Kinase +4

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader

Hai‐Tsang Huang, Dennis Dobrovolsky, Joshiawa Paulk et al. · Cell chemical biology · 2017 · 431 citations · Full text

Protein Function, Chemoproteomic Approach, Structural Bioinformatics +13

SAICAR Induces Protein Kinase Activity of PKM2 that Is Necessary for Sustained Proliferative Signaling of Cancer Cells

Kirstie E. Keller, Zainab M. Doctor, Zachary W. Dwyer et al. · Molecular Cell · 2014 · 175 citations · Full text

Sustained Proliferative Signaling, Cancer Research, Signal Transduction +11

Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells

Shingo Kozono, Yu‐Min Lin, Hyuk‐Soo Seo et al. · Nature Communications · 2018 · 159 citations · Full text

Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

Christian Dubiella, Benika J. Pinch, Kazuhiro Koikawa et al. · Nature Chemical Biology · 2021 · 141 citations · Full text

Covalent Inhibitor, Oncology, Malignant Disease +9