Yanke Liang

Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation

Baishan Jiang, Michael A. Erb, Yanke Liang et al. · Nature Chemical Biology · 2017 · 531 citations · Full text

Selective Cdk9 Inhibition, Medicine, Receptor Tyrosine Kinase +4

Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors

Tinghu Zhang, Nicholas Kwiatkowski, Sarah E. Dixon-Clarke et al. · Nature Chemical Biology · 2016 · 356 citations · Full text

Drug Target, Drug Targeting, Biochemistry +10

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

Katherine A. Donovan, Fleur M. Ferguson, Jonathan W. Bushman et al. · Cell · 2020 · 346 citations · Full text

Geometric Modeling, Robotics, Engineering +11

Development of Dual and Selective Degraders of Cyclin‐Dependent Kinases 4 and 6

Baishan Jiang, Eric S. Wang, Katherine A. Donovan et al. · Angewandte Chemie International Edition · 2019 · 253 citations · Full text

Chemoprevention Strategy, Molecular Regulation, Molecular Biology +20

Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML

Matthias Brand, Baishan Jiang, Sophie Bauer et al. · Cell chemical biology · 2018 · 244 citations · Full text

Natural Sciences, Molecular Biology, Homolog-selective Degradation +2