Tinghu Zhang

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn et al. · Nature · 2012 · 2.5K citations · Full text

Systematic Identification, Genomic Markers, Engineering +12

A Landscape of Pharmacogenomic Interactions in Cancer

Francesco Iorio, Theo Knijnenburg, Daniël J. Vis et al. · Cell · 2016 · 2.2K citations · Full text

Tumor Biology, Oncology, Tumor Heterogeneity +13

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

Nicholas Kwiatkowski, Tinghu Zhang, Peter B. Rahl et al. · Nature · 2014 · 882 citations · Full text

CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

Edmond Chipumuro, Eugenio Marco, Camilla L. Christensen et al. · Cell · 2014 · 641 citations · Full text

Medicine, Mycn-driven Cancer, Tumor Suppressor +3

Plasticity in binding confers selectivity in ligand-induced protein degradation

Radosław P. Nowak, Stephen L. DeAngelo, Dennis L. Buckley et al. · Nature Chemical Biology · 2018 · 609 citations · Full text

Protein Chemistry, Biochemistry, Protein Assembly +5