Radosław P. Nowak

Plasticity in binding confers selectivity in ligand-induced protein degradation

Radosław P. Nowak, Stephen L. DeAngelo, Dennis L. Buckley et al. · Nature Chemical Biology · 2018 · 609 citations · Full text

Protein Chemistry, Biochemistry, Protein Assembly +5

Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome

Katherine A. Donovan, An Jian, Radosław P. Nowak et al. · eLife · 2018 · 502 citations · Full text

Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance

Wen Zhou, Aaron T. Whiteley, Carina C. de Oliveira Mann et al. · Cell · 2018 · 366 citations · Full text

Immunogenetics, Innate Immune System, Immunology +8

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

Nicholas M. Pearce, T. Krojer, A.R. Bradley et al. · Nature Communications · 2017 · 318 citations · Full text

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

Mei Zeng, Yuan Xiong, Nozhat Safaee et al. · Cell chemical biology · 2019 · 266 citations · Full text

Oncogenic Agent, Molecular Biology, Degradation Reaction +3