Nozhat Safaee

Plasticity in binding confers selectivity in ligand-induced protein degradation

Radosław P. Nowak, Stephen L. DeAngelo, Dennis L. Buckley et al. · Nature Chemical Biology · 2018 · 609 citations · Full text

Protein Chemistry, Biochemistry, Protein Assembly +5

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

Mei Zeng, Yuan Xiong, Nozhat Safaee et al. · Cell chemical biology · 2019 · 266 citations · Full text

Oncogenic Agent, Molecular Biology, Degradation Reaction +3

Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G

Nozhat Safaee, Guennadi Kozlov, Anne M. Noronha et al. · Molecular Cell · 2012 · 127 citations · Full text

Natural Sciences, Rna Biology, Molecular Biology +6

Structural Basis of Binding of P-body-associated Proteins GW182 and Ataxin-2 by the Mlle Domain of Poly(A)-binding Protein

Guennadi Kozlov, Nozhat Safaee, Angelika Rosenauer et al. · Journal of Biological Chemistry · 2010 · 101 citations · Full text

Protein Assembly, Molecular Biology, Rna Binding Proteins +19

Exploring the target scope of KEAP1 E3 ligase-based PROTACs

Guangyan Du, Jie Jiang, Nathaniel J. Henning et al. · Cell chemical biology · 2022 · 82 citations · Full text

Protein Function, Natural Sciences, Molecular Biology +4