Wen Zhou

Activation of Necroptosis in Multiple Sclerosis

Dimitry Ofengeim, Yasushi Ito, Ayaz Najafov et al. · Cell Reports · 2015 · 508 citations · Full text

Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance

Wen Zhou, Aaron T. Whiteley, Carina C. de Oliveira Mann et al. · Cell · 2018 · 366 citations · Full text

Immunogenetics, Innate Immune System, Immunology +8

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA

Katherine C. Barnett, Julia María Coronas-Serna, Wen Zhou et al. · Cell · 2019 · 266 citations · Full text

Viral Dna, Viral Replication, Proteinlipid Interaction +10

A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions

Marta M. Lipinski, Greg Hoffman, Aylwin Ng et al. · Developmental Cell · 2010 · 221 citations · Full text

Cell Autophagy, Mitophagy, Signaling Pathway +9

cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila

Kailey M. Slavik, Benjamin R. Morehouse, Adelyn E. Ragucci et al. · Nature · 2021 · 182 citations · Full text