Joshiawa Paulk

Phthalimide conjugation as a strategy for in vivo target protein degradation

Georg E. Winter, Dennis L. Buckley, Joshiawa Paulk et al. · Science · 2015 · 1.7K citations · Full text

The dTAG system for immediate and target-specific protein degradation

Behnam Nabet, Justin M. Roberts, Dennis L. Buckley et al. · Nature Chemical Biology · 2018 · 1.1K citations · Full text

Protein Function, Protein Expression, Protein Folding +6

<i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

Gregory V. Kryukov, Frederick H. Wilson, Jason R. Ruth et al. · Science · 2016 · 608 citations

Epigenetic Change, Molecular Biology, Prmt5 Arginine Methyltransferase +20

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

Georg Winter, Andreas Mayer, Dennis L. Buckley et al. · Molecular Cell · 2017 · 467 citations · Full text

Transcriptional Regulation, Cell Regulation, Genetics +7

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader

Hai‐Tsang Huang, Dennis Dobrovolsky, Joshiawa Paulk et al. · Cell chemical biology · 2017 · 431 citations · Full text

Protein Function, Chemoproteomic Approach, Structural Bioinformatics +13