<i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

Gregory V. Kryukov, Frederick H. Wilson, Jason R. Ruth, +18

Science

Epigenetic ChangeMolecular BiologyPrmt5 Arginine MethyltransferaseCancer BiologyEpigenetics +18

International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease

David C. Fajgenbaum, Thomas S. Uldrick, Adam Bagg, +35

Blood

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease

Frits van Rhee, Peter M. Voorhees, Angela Dispenzieri, +39

Blood

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

Mark A. LaBarge, Celeste M. Nelson, René Villadsen, +5

Integrative Biology

Combinatorial MicroenvironmentsBiological MicroenvironmentsReproductive BiologyCell SpecializationMammary Gland Development +16

Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6 blockade–refractory idiopathic multicentric Castleman disease

David C. Fajgenbaum, Ruth-Anne Langan, Alberto Sada Japp, +20

Journal of Clinical Investigation

Cytokine responses during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Production of Th1 and Th2 cytokines and relative contribution of tumor necrosis factor.

Stephen W. Chensue, Kelly Warmington, Jason R. Ruth, +3

PubMed

Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy

James V. Alvarez, Tien-Chi Pan, Jason R. Ruth, +7

Cancer Cell

Systems BiologyEngineeringBreast OncologyMedicineCancer Genomics +8

Plasma proteomics identifies a ‘chemokine storm’ in idiopathic multicentric Castleman disease

Sheila K. Pierson, Aaron J. Stonestrom, Dustin Shilling, +8

American Journal of Hematology

Non-invasive tissue temperature measurements based on quantitative diffuse optical spectroscopy (DOS) of water

So Hyun Chung, Albert E. Cerussi, Sean Merritt, +2

Physics in Medicine and Biology

EngineeringThermographyInfrared SpectroscopySpectroscopyThermistor Measurements +12

SPSB1 Promotes Breast Cancer Recurrence by Potentiating c-MET Signaling

Yi Feng, Tien-Chi Pan, Dhruv K. Pant, +4

Cancer Discovery