Shingo Kozono

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

Shuo Wei, Shingo Kozono, Lev M. Kats et al. · Nature Medicine · 2015 · 265 citations · Full text

Active Pin1, Mixed-phenotype Acute Leukemia, Breast Cancer +6

Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells

Shingo Kozono, Kenoki Ohuchida, Daiki Eguchi et al. · Cancer Research · 2013 · 194 citations

Pancreatic Cancer, Medicine, Primary Pscs +13

Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells

Shingo Kozono, Yu‐Min Lin, Hyuk‐Soo Seo et al. · Nature Communications · 2018 · 159 citations · Full text

Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

Christian Dubiella, Benika J. Pinch, Kazuhiro Koikawa et al. · Nature Chemical Biology · 2021 · 141 citations · Full text

Covalent Inhibitor, Oncology, Malignant Disease +9

Identification of a potent and selective covalent Pin1 inhibitor

Benika J. Pinch, Zainab M. Doctor, Behnam Nabet et al. · Nature Chemical Biology · 2020 · 83 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +4