Nadine Hein

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

Megan J. Bywater, Gretchen Poortinga, Elaine Sanij et al. · Cancer Cell · 2012 · 560 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

Per Hydbring, Fuad Bahram, Yingtao Su et al. · Proceedings of the National Academy of Sciences · 2009 · 239 citations · Full text

Medicine, Cell Biology, Oncology +17

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

Amit Khot, Natalie Brajanovski, Donald P. Cameron et al. · Cancer Discovery · 2019 · 203 citations

Medicine, Oncology, Pharmacology +15

Identification of<i>Burkholderia pseudomallei</i>Genes Required for the Intracellular Life Cycle and In Vivo Virulence

Sabine Pilatz, Katrin Breitbach, Nadine Hein et al. · Infection and Immunity · 2006 · 185 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

Jennifer R. Devlin, Katherine M. Hannan, Nadine Hein et al. · Cancer Discovery · 2015 · 127 citations · Full text

Life Sciences, Oncology, Pharmacology +17