Katherine M. Hannan

mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF†

Katherine M. Hannan, Yves Brandenburger, Anna Jenkins et al. · Molecular and Cellular Biology · 2003 · 456 citations · Full text

Transcriptional Regulation, Systems Biology, Cell Regulation +15

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy

Megan V. Astle, Katherine M. Hannan, Puiyee Ng et al. · Oncogene · 2011 · 278 citations · Full text

AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer

Joanna C. Chan, Katherine M. Hannan, Kim Riddell et al. · Science Signaling · 2011 · 236 citations

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Elaine Sanij, Katherine M. Hannan, Jiachen Xuan et al. · Nature Communications · 2020 · 213 citations · Full text

UBF levels determine the number of active ribosomal RNA genes in mammals

Elaine Sanij, Gretchen Poortinga, Kerith Sharkey et al. · The Journal of Cell Biology · 2008 · 207 citations · Full text