Concepedia

Author

Elaine Sanij

Peter MacCallum Cancer CentreORCID

Also Known As

David D. L. Bowtell, E Sanij, E. Sanij, Elaine P. Sanij, Elaine Sanij, Sanij, Elaine

110

Publications

4.8K

Citations

31

H-Index

50

Concepts

All Affiliations

Peter MacCallum Cancer CentreThe University of MelbourneMonash UniversityThe University of QueenslandAustralian National University
ES

About

Elaine Sanij is an author at Peter MacCallum Cancer Centre specializing in medicine, cell biology, and transcriptional regulation.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

11

11

785

2

Cell Biology

10

10

713

3

Natural Sciences

4

4

371

4

Immunology

3

3

132

5

Molecular Biology

2

2

184

Elaine Sanij

×

33

Publications

3.6K

Citations

25

H-Index

YearCitations

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

Denis Drygin, Amy Lin, Josh Bliesath,

Cancer Research

2010

610

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

Megan J. Bywater, Gretchen Poortinga, Elaine Sanij,

Cancer Cell

2012

552

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

Olga Kondrashova, Monique Topp, Ksenija Nesic,

Nature Communications

2018

277

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Elaine Sanij, Katherine M. Hannan, Jiachen Xuan,

Nature Communications

2020

213

UBF levels determine the number of active ribosomal RNA genes in mammals

Elaine Sanij, Gretchen Poortinga, Kerith Sharkey,

The Journal of Cell Biology

2008

207

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

Amit Khot, Natalie Brajanovski, Donald P. Cameron,

Cancer Discovery

2019

197

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

Jennifer R. Devlin, Katherine M. Hannan, Nadine Hein,

Cancer Discovery

2015

125

Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

Shatha AbuHammad, Carleen Cullinane, Claire Martin,

Proceedings of the National Academy of Sciences

2019

116

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

Jaclyn Quin, Keefe T. Chan, Jennifer R. Devlin,

Oncotarget

2016

114

Widespread FRA1-Dependent Control of Mesenchymal Transdifferentiation Programs in Colorectal Cancer Cells

Jeannine Diesch, Elaine Sanij, Omer Gilan,

PLoS ONE

2014

103

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