Gretchen Poortinga

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

Megan J. Bywater, Gretchen Poortinga, Elaine Sanij et al. · Cancer Cell · 2012 · 552 citations · Full text

mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF†

Katherine M. Hannan, Yves Brandenburger, Anna Jenkins et al. · Molecular and Cellular Biology · 2003 · 456 citations · Full text

Transcriptional Regulation, Systems Biology, Cell Regulation +15

Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and Hairy-mediated transcriptional repression

Gretchen Poortinga, Minoru Watanabe, Susan M. Parkhurst · The EMBO Journal · 1998 · 244 citations · Full text

Transcriptional Regulation, Developmental Biology, Developmental Genetics +11

AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer

Joanna C. Chan, Katherine M. Hannan, Kim Riddell et al. · Science Signaling · 2011 · 236 citations

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Elaine Sanij, Katherine M. Hannan, Jiachen Xuan et al. · Nature Communications · 2020 · 213 citations · Full text