Direct observation of individual endogenous protein complexes in situ by proximity ligation

Ola Söderberg, Mats Gullberg, Malin Jarvius, +8

Nature Methods

Protein ChemistryProtein FunctionProximity LigationProtein AssemblyBiochemistry +6

A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells

Lars Anders, Nan Rosemary Ke, Per Hydbring, +8

Cancer Cell

Tumor BiologySystematic ScreenSignal TransductionSignaling PathwayCell Regulation +12

The F-Box Protein Skp2 Participates in c-Myc Proteosomal Degradation and Acts as a Cofactor for c-Myc-Regulated Transcription

Natalie von der Lehr, Sara Johansson, Siqin Wu, +10

Molecular Cell

Transcriptional RegulationCell RegulationMedicineNatural SciencesMolecular Biology +10

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription

Azadeh Arabi, Siqin Wu, Karin Ridderstråle, +9

Nature Cell Biology

Ribosomal DnaTranscriptional RegulationNatural SciencesC-myc AssociatesRna Polymerase +11

The Requirement for Cyclin D Function in Tumor Maintenance

Yoon Jong Choi, Xiaoyu Li, Per Hydbring, +8

Cancer Cell

OncologyMedicinePathologyAnti-cancer AgentCyclin D Function +4

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop

Antje Menssen, Per Hydbring, Karsten Kapelle, +5

Proceedings of the National Academy of Sciences

Cdk2 suppresses cellular senescence induced by the c-myc oncogene

Stefano Campaner, Mirko Doni, Per Hydbring, +11

Nature Cell Biology

Signal TransductionCell RegulationC-myc OncogeneCellular SenescenceCell Cycle +3

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

Per Hydbring, Fuad Bahram, Yingtao Su, +12

Proceedings of the National Academy of Sciences

Activated MycCell DeathCell CycleCdk2 ActivityCancer Biology +17

PHGDH Defines a Metabolic Subtype in Lung Adenocarcinomas with Poor Prognosis

Boxi Zhang, Adi Zheng, Per Hydbring, +5

Cell Reports

Metabolic DependenciesPathologyMolecular BiologyMetabolic RemodelingTumor Biology +17

Clinical applications of microRNAs

Per Hydbring, Gayane Badalian‐Very

F1000Research

EngineeringPathologyDiagnostic MicrornasMolecular TherapiesEpigenetics +15