Direct observation of individual endogenous protein complexes in situ by proximity ligation

Ola Söderberg, Mats Gullberg, Malin Jarvius, +8

Nature Methods

Protein ChemistryProtein FunctionProximity LigationProtein AssemblyBiochemistry +6

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

Ola Söderberg, Karl‐Johan Leuchowius, Mats Gullberg, +4

Methods

Protein FunctionProtein AssemblyBiochemistryProtein FoldingNatural Sciences +9

Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Anna Segerman, Mia Niklasson, Caroline Haglund, +18

Cell Reports

Clonal VariationNeural Stem CellHigh-grade GliomasCancer BiologyGlioma +19

In Situ Detection of Phosphorylated Platelet-derived Growth Factor Receptor β Using a Generalized Proximity Ligation Method

Malin Jarvius, Janna Paulsson, Irene Weibrecht, +10

Molecular & Cellular Proteomics

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

Ingrid Nilsson, Fuad Bahram, Xiujuan Li, +12

The EMBO Journal

Developmental BiologyAngiogenesisProximity LigationAngiogenic SproutsMorphogenesis +7

Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors

Hannah Karlsson, Emma Svensson, Camilla Gigg, +5

PLoS ONE

Car T CellsImmunocytochemical TechniqueSignal TransductionAutoimmune DiseaseT-regulatory Cell +11

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nadilly Bonagas, Nina Gustafsson, Martin Henriksson, +65

Nature Cancer

High Content Screening for Inhibitors of Protein Interactions and Post-translational Modifications in Primary Cells by Proximity Ligation

Karl‐Johan Leuchowius, Malin Jarvius, Malin Wickström, +6

Molecular & Cellular Proteomics

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

Yiwen Jiang, Voichita D. Marinescu, Yuan Xie, +13

Cell Reports

Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia

Anna Eriksson, Albin Österroos, Syed Shams ul Hassan, +7

Blood Cancer Journal