Meng Fang

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 210 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Lysosomal Storage Disorder +11

Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme

Annie Arguello, Cathal Mahon, Meredith Calvert et al. · The Journal of Experimental Medicine · 2021 · 80 citations · Full text

Immunology, Synaptic Signaling, Social Sciences +22

Central Role of the EGF Receptor in Neurometabolic Aging

Sana Siddiqui, Meng Fang, Bin Ni et al. · International Journal of Endocrinology · 2012 · 58 citations · Full text

Aging, Egfr Signaling, Cellular Physiology +17

Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients

Akhil Bhalla, Ritesh Ravi, Meng Fang et al. · International Journal of Molecular Sciences · 2020 · 29 citations · Full text

Pathology, Neurochemical Biomarkers, Neuroinflammation +16

Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome

Annie Arguello, René Meisner, Elliot R. Thomsen et al. · JCI Insight · 2021 · 29 citations · Full text

Immunology, Mucopolysaccharidosis Type Ii, Cellular Physiology +20