Ritesh Ravi

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 210 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Lysosomal Storage Disorder +11

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice

Julie C. Ullman, Annie Arguello, Jennifer A. Getz et al. · Science Translational Medicine · 2020 · 194 citations

Molecular Neuroscience, Blood–brain Barrier, Medicine +15

Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients

Akhil Bhalla, Ritesh Ravi, Meng Fang et al. · International Journal of Molecular Sciences · 2020 · 29 citations · Full text

Pathology, Neurochemical Biomarkers, Neuroinflammation +16

Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome

Annie Arguello, René Meisner, Elliot R. Thomsen et al. · JCI Insight · 2021 · 29 citations · Full text

Immunology, Mucopolysaccharidosis Type Ii, Cellular Physiology +20

High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II

Junhua Wang, Akhil Bhalla, Julie C. Ullman et al. · International Journal of Molecular Sciences · 2020 · 18 citations · Full text

Csf Gags, Immunology, Biological Mass Spectrometry +23