Conserved cell types with divergent features in human versus mouse cortex

Rebecca D. Hodge, Trygve E. Bakken, Jeremy A. Miller, +60

Nature

Human CellCellular NeurobiologyDevelopmental BiologyConserved Cell TypesCellular Neuroscience +10

Human neocortical expansion involves glutamatergic neuron diversification

Jim Berg, Staci A. Sorensen, Jonathan T. Ting, +142

Nature

Fixed single-cell transcriptomic characterization of human radial glial diversity

Elliot R. Thomsen, John K. Mich, Zizhen Yao, +8

Nature Methods

BioinformaticsFunctional GenomicsSingle Cell SequencingMedicineGenetics +7

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

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Nature Neuroscience

A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development

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Cell stem cell

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Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia

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Molecular Neurodegeneration

Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme

Annie Arguello, Cathal Mahon, Meredith Calvert, +30

The Journal of Experimental Medicine

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High-Resolution Analysis and Functional Mapping of Cleavage Sites and Substrate Proteins of Furin in the Human Proteome

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PLoS ONE

Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation

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Neuron

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New Details of HCV NS3/4A Proteinase Functionality Revealed by a High-Throughput Cleavage Assay

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PLoS ONE