Vittorio Rasetti

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 502 citations

Combinatorial Chemistry, Pharmaceutical Science, Biochemistry +7

Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin

Joseph Rahuel, Vittorio Rasetti, Jürgen Maibaum et al. · Chemistry & Biology · 2000 · 320 citations · Full text

Drug Target, Biochemistry, Drug Design +11

Synthesis and biological activity of some transition-state inhibitors of human renin

Peter Bühlmayer, Walter Fuhrer, Richard Göschke et al. · Journal of Medicinal Chemistry · 1988 · 111 citations · Full text

Ring contraction of hydroporphinoid to corrinoid complexes

Vittorio Rasetti, Andreas Pfaltz, Christoph Kratky et al. · Proceedings of the National Academy of Sciences · 1981 · 51 citations · Full text

Novel 2,7-Dialkyl-Substituted 5(<i>S</i>)-Amino-4(<i>S</i>)-hydroxy-8-phenyl-octanecarboxamide Transition State Peptidomimetics Are Potent and Orally Active Inhibitors of Human Renin

Richard Göschke, Stefan Stutz, Vittorio Rasetti et al. · Journal of Medicinal Chemistry · 2007 · 49 citations · Full text

Hypertension, Novel 2,7-Dialkyl-substituted 5, Pharmacotherapy +17