Concepedia

Richard Göschke

RG

11

Publications

1.3K

Citations

11

H-Index

1964

Active since

Affiliations

Novartis (Switzerland)(Current)

Novartis Institutes for BioMedical Research

Richard Göschke is an author at Novartis (Switzerland) specializing in pharmacology, drug discovery, and medicine.

Top concepts

Publications per year

1964–2007

11

Publications

11

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 502 citations

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Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin

Joseph Rahuel, Vittorio Rasetti, Jürgen Maibaum et al. · Chemistry & Biology · 2000 · 320 citations · Full text

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Synthesis and biological activity of some transition-state inhibitors of human renin

Peter Bühlmayer, Walter Fuhrer, Richard Göschke et al. · Journal of Medicinal Chemistry · 1988 · 111 citations · Full text

Structural Modification of the P2‘ Position of 2,7-Dialkyl-Substituted 5( <i>S</i> )-Amino-4( <i>S</i> )-hydroxy-8-phenyl-octanecarboxamides:  The Discovery of Aliskiren, a Potent Nonpeptide Human Renin Inhibitor Active after Once Daily Dosing in Marmosets

Jürgen Maibaum, Stefan Stutz, Richard Göschke et al. · Journal of Medicinal Chemistry · 2007 · 95 citations · Full text

Total synthesis of the calycanthaceous alkaloids

James B. Hendrickson, Richard Göschke, R. W. Rees · Tetrahedron · 1964 · 91 citations

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