Concepedia

Jürgen Maibaum

JM

Statistics

Publications

25

Citations

1.8K

H-Index

20

Active since

1985

Affiliations

Novartis (Switzerland)(Current)

Novartis Institutes for BioMedical Research

Novartis (United States)

Novartis (Japan)

University of Münster

Jürgen Maibaum is an author at Novartis (Switzerland) specializing in medicinal chemistry, pharmacology, and drug discovery.

Publications per year

1985–2024

25

Publications

25

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 503 citations

, , +14

Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin

Joseph Rahuel, Vittorio Rasetti, Jürgen Maibaum et al. · Chemistry & Biology · 2000 · 321 citations · Full text

, , +16

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Anna Schubart, Karen Anderson, Nello Mainolfi et al. · Proceedings of the National Academy of Sciences · 2019 · 216 citations · Full text

, , +17

Structural Modification of the P2‘ Position of 2,7-Dialkyl-Substituted 5( <i>S</i> )-Amino-4( <i>S</i> )-hydroxy-8-phenyl-octanecarboxamides:  The Discovery of Aliskiren, a Potent Nonpeptide Human Renin Inhibitor Active after Once Daily Dosing in Marmosets

Jürgen Maibaum, Stefan Stutz, Richard Göschke et al. · Journal of Medicinal Chemistry · 2007 · 95 citations · Full text

, , +13

Small-molecule factor D inhibitors targeting the alternative complement pathway

Jürgen Maibaum, Sha-Mei Liao, Anna Vulpetti et al. · Nature Chemical Biology · 2016 · 75 citations · Full text

, , +14

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