Novartis (Japan)

Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients

Masayuki Takahashi, Osamu Shirakawa, Kazuhiko Toyooka et al. · Molecular Psychiatry · 2000 · 342 citations

Neuropsychology, Psychiatry, Neurophysiology +13

Human Heparanase

Minako Toyoshima, Motowo Nakajima · Journal of Biological Chemistry · 1999 · 298 citations · Full text

Cell–matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca2+ influx and PKC activation

Osamu Nagano, Daizo Murakami, Dieter Hartmann et al. · The Journal of Cell Biology · 2004 · 285 citations · Full text

Cell Adhesion, Immunology, Molecular Biology +22

CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration

Isamu Okamoto, Yoshiaki Kawano, Hiromasa Tsuiki et al. · Oncogene · 1999 · 254 citations

Cd44 Cleavage, Membrane-associated Metalloprotease, Medicine +13

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Anna Schubart, Karen Anderson, Nello Mainolfi et al. · Proceedings of the National Academy of Sciences · 2019 · 206 citations · Full text

Immunology, Biological Therapy, Dermatology +23