Isamu Okamoto

Human Ect2 Is an Exchange Factor for Rho Gtpases, Phosphorylated in G2/M Phases, and Involved in Cytokinesis

Takashi Tatsumoto, Xiaozhen Xie, Rayah Blumenthal et al. · The Journal of Cell Biology · 1999 · 427 citations · Full text

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

Isamu Okamoto, Yoshiaki Kawano, Daizo Murakami et al. · The Journal of Cell Biology · 2001 · 367 citations · Full text

CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration

Isamu Okamoto, Yoshiaki Kawano, Hiromasa Tsuiki et al. · Oncogene · 1999 · 254 citations

Cd44 Cleavage, Membrane-associated Metalloprotease, Medicine +13

Proteolytic Cleavage of the CD44 Adhesion Molecule in Multiple Human Tumors

Isamu Okamoto, Hiromasa Tsuiki, Lawrence C. Kenyon et al. · American Journal Of Pathology · 2002 · 157 citations · Full text

Tumor Biology, Proteolytic Cleavage, Cd44 Adhesion Molecule +9

Presenilin-dependent γ-secretase activity mediates the intramembranous cleavage of CD44

Daizo Murakami, Isamu Okamoto, Osamu Nagano et al. · Oncogene · 2003 · 148 citations

Presenilin-dependent γ-Secretase Activity, Protein Secretion, Signal Transduction +9