Osamu Irie

Further Studies on Total Synthesis of Sarain A. Efforts Toward Annulation of the Macrocyclic Rings

Osamu Irie, Kiyohiro Samizu, James R. Henry et al. · The Journal of Organic Chemistry · 1998 · 51 citations

Novel scaffold for cathepsin K inhibitors

Naoki Teno, Takahiro Miyake, Takeru Ehara et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 41 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +4

Discovery of Orally Bioavailable Cathepsin S Inhibitors for the Reversal of Neuropathic Pain

Osamu Irie, Takatoshi Kosaka, Takeru Ehara et al. · Journal of Medicinal Chemistry · 2008 · 39 citations · Full text

Inflammation, Pain Therapy, Medicinal Chemistry +15

2-Cyano-pyrimidines:  A New Chemotype for Inhibitors of the Cysteine Protease Cathepsin K

Eva Altmann, Reiner Aichholz, Claudia Betschart et al. · Journal of Medicinal Chemistry · 2007 · 35 citations · Full text

Combinatorial Chemistry, Pharmaceutical Science, Bioorganic Chemistry +17

An efficient total synthesis of (−)-mintlactone and (+)-isomintlactone

Kozo Shishido, Osamu Irie, Masayuki Shibuya · Tetrahedron Letters · 1992 · 33 citations

Pharmacology, Efficient Total Synthesis, Enantioselective Synthesis