Takeru Ehara

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Anna Schubart, Karen Anderson, Nello Mainolfi et al. · Proceedings of the National Academy of Sciences · 2019 · 206 citations · Full text

Immunology, Biological Therapy, Dermatology +23

Discovery of 4-((2 <i>S</i> ,4 <i>S</i> )-4-Ethoxy-1-((5-methoxy-7-methyl-1 <i>H</i> -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases

Nello Mainolfi, Takeru Ehara, Rajeshri G. Karki et al. · Journal of Medicinal Chemistry · 2020 · 57 citations

Peptide Binder to Glypican-3 as a Theranostic Agent for Hepatocellular Carcinoma

Fanching Lin, Renee Clift, Takeru Ehara et al. · Journal of Nuclear Medicine · 2024 · 43 citations · Full text

Novel scaffold for cathepsin K inhibitors

Naoki Teno, Takahiro Miyake, Takeru Ehara et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 41 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +4

Discovery of Orally Bioavailable Cathepsin S Inhibitors for the Reversal of Neuropathic Pain

Osamu Irie, Takatoshi Kosaka, Takeru Ehara et al. · Journal of Medicinal Chemistry · 2008 · 39 citations · Full text

Inflammation, Pain Therapy, Medicinal Chemistry +15