Rajeshri G. Karki - Concepedia

Author

Rajeshri G. Karki

Also Known As

Karki, R.G., R. G. Karki, R. Karki, Rajeshri G Karki, Rajeshri G. Karki, Rajeshri Karki, Rajeshri?G. Karki, Ranjana Karki

Publications

1.8K

Citations

H-Index

Concepts

All Affiliations

Novartis (Switzerland)Novartis (United States)National Cancer Institute National Institutes of Health Novartis Institutes for BioMedical Research

About

Rajeshri G. Karki is an author at Novartis (Switzerland) specializing in medicine, drug discovery, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	14	1K
2	Natural Sciences	8	8	618
3	Biochemistry	7	7	213
4	Engineering	5	5	188
5	Allergy	1	1	206

Rajeshri G. Karki

Publications

1.6K

Citations

H-Index

Page 1

	Year	Citations
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex Dirksen E. Bussiere, Lili Xie, Honnappa Srinivas, Nature Chemical Biology Signal TransductionMolecular ResearchMolecular RegulationMedicineNatural Sciences	2019	243
Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers Julien P. N. Papillon, Katsumasa Nakajima, Christopher D. Adair, Journal of Medicinal Chemistry Brahma HomologMolecular BiologyCancer BiologyTumor BiologyTranscriptional Regulation	2018	225
Small-molecule factor B inhibitor for the treatment of complement-mediated diseases Anna Schubart, Karen Anderson, Nello Mainolfi, Proceedings of the National Academy of Sciences ImmunologyBiological TherapyDermatologyImmunotherapyInflammation	2019	206
Metal-Dependent Inhibition of HIV-1 Integrase by β-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S) Christophe Marchand, Allison A. Johnson, Rajeshri G. Karki, Molecular Pharmacology	2003	132
Medicinal Chemistry Profiling of Monocyclic 1,2‐Azaborines Peng Zhao, David O. Nettleton, Rajeshri G. Karki, ChemMedChem	2017	114
Structure of neprilysin in complex with the active metabolite of sacubitril Nikolaus Schiering, A. D’Arcy, Frédéric Villard, Scientific Reports	2016	66
PDB Ligand Conformational Energies Calculated Quantum-Mechanically Markus Sitzmann, Iwona E. Weidlich, Igor Filippov, Journal of Chemical Information and Modeling Ligand Expo DatabaseEngineeringConformational EnergiesBiochemistryMedicine	2012	63
Discovery of 4-((2 <i>S</i> ,4 <i>S</i> )-4-Ethoxy-1-((5-methoxy-7-methyl-1 <i>H</i> -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases Nello Mainolfi, Takeru Ehara, Rajeshri G. Karki, Journal of Medicinal Chemistry	2020	57
Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design Rajeshri G. Karki, Yun Tang, Terrence R. Burke, Journal of Computer-Aided Molecular Design Viral DnaHuman RetrovirusAntiviral Drug DevelopmentMolecular BiologyVirology	2004	56
Application of azide–alkyne cycloaddition ‘click chemistry’ for the synthesis of Grb2 SH2 domain-binding macrocycles Won Jun Choi, Zhendan Shi, Karen M. Worthy, Bioorganic & Medicinal Chemistry Letters HeterocyclicBiochemistryNatural SciencesOrganic ChemistryClick Chemistry	2006	43

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