Rajeshri G. Karki

Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

Dirksen E. Bussiere, Lili Xie, Honnappa Srinivas et al. · Nature Chemical Biology · 2019 · 243 citations

Signal Transduction, Molecular Research, Molecular Regulation +10

Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers

Julien P. N. Papillon, Katsumasa Nakajima, Christopher D. Adair et al. · Journal of Medicinal Chemistry · 2018 · 225 citations · Full text

Brahma Homolog, Molecular Biology, Cancer Biology +19

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Anna Schubart, Karen Anderson, Nello Mainolfi et al. · Proceedings of the National Academy of Sciences · 2019 · 206 citations · Full text

Immunology, Biological Therapy, Dermatology +23

Metal-Dependent Inhibition of HIV-1 Integrase by β-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S)

Christophe Marchand, Allison A. Johnson, Rajeshri G. Karki et al. · Molecular Pharmacology · 2003 · 132 citations

Medicinal Chemistry Profiling of Monocyclic 1,2‐Azaborines

Peng Zhao, David O. Nettleton, Rajeshri G. Karki et al. · ChemMedChem · 2017 · 114 citations · Full text