Claudia Betschart

Identification of a Novel Series of Orexin Receptor Antagonists with a Distinct Effect on Sleep Architecture for the Treatment of Insomnia

Claudia Betschart, Samuel Hintermann, Dirk Behnke et al. · Journal of Medicinal Chemistry · 2013 · 103 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

Jonathan H. Fox, Teal Connor, Vanita Chopra et al. · Molecular Neurodegeneration · 2010 · 96 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Structure-Based Design, Synthesis, and Memapsin 2 (BACE) Inhibitory Activity of Carbocyclic and Heterocyclic Peptidomimetics

Stephen Hanessian, Hongying Yun, Yihua Hou et al. · Journal of Medicinal Chemistry · 2005 · 73 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis of azapenams, diazepinones, and dioxocyclams via the photolytic reaction of chromium alkoxycarbene complexes with imidazolines

Claudia Betschart, Louis S. Hegedus · Journal of the American Chemical Society · 1992 · 72 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Anwendungsbreite der reduktiven Kupplung aromatischer Aldimin‐Derivate mit niedervalenten Titan‐Reagenzien zu 1,2‐Diarylethylendiaminen

Claudia Betschart, Beat Schmidt, Dieter Seebàch · Helvetica Chimica Acta · 1988 · 71 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8