Concepedia

Stefan Stutz

SS

Statistics

Publications

15

Citations

1.5K

H-Index

13

Active since

1991

Affiliations

Novartis (Switzerland)(Current)

Novartis Institutes for BioMedical Research

Stefan Stutz is an author at Novartis (Switzerland) specializing in drug discovery, medicinal chemistry, and pharmacology.

Publications per year

1991–2019

15

Publications

15

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 503 citations

, , +14

Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin

Joseph Rahuel, Vittorio Rasetti, Jürgen Maibaum et al. · Chemistry & Biology · 2000 · 321 citations · Full text

, , +16

Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors

Philipp Holzer, Keiichi Masuya, Pascal Furet et al. · Journal of Medicinal Chemistry · 2015 · 206 citations · Full text

, , +15

Structural Modification of the P2‘ Position of 2,7-Dialkyl-Substituted 5( <i>S</i> )-Amino-4( <i>S</i> )-hydroxy-8-phenyl-octanecarboxamides:  The Discovery of Aliskiren, a Potent Nonpeptide Human Renin Inhibitor Active after Once Daily Dosing in Marmosets

Jürgen Maibaum, Stefan Stutz, Richard Göschke et al. · Journal of Medicinal Chemistry · 2007 · 95 citations · Full text

, , +13

Discovery of a novel class of highly potent inhibitors of the p53–MDM2 interaction by structure-based design starting from a conformational argument

Pascal Furet, Keiichi Masuya, Joerg Kallen et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 79 citations

, , +10

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