Lixin Wan

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama et al. · Nature · 2011 · 628 citations · Full text

Signaling Pathway, Cell Regulation, Apoptosis +6

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

Pengda Liu, Michael J. Begley, Wojciech Michowski et al. · Nature · 2014 · 363 citations · Full text

Signal Transduction, Cell Regulation, Biochemistry +13

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

Yu-Ru Lee, Ming Chen, Jonathan D. Lee et al. · Science · 2019 · 329 citations

Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

Antonella Papa, Lixin Wan, Massimo Bonora et al. · Cell · 2014 · 266 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +9

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

Pengda Liu, Wenjian Gan, Hiroyuki Inuzuka et al. · Nature Cell Biology · 2013 · 253 citations · Full text