Christof Fellmann

An Optimized microRNA Backbone for Effective Single-Copy RNAi

Christof Fellmann, Thomas Hoffmann, Vaishali Sridhar et al. · Cell Reports · 2013 · 738 citations · Full text

Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors

Tony P. Huang, Kevin T. Zhao, Shannon M. Miller et al. · Nature Biotechnology · 2019 · 316 citations

Engineering, Pam-modified Cas9 Variants, Molecular Biology +6

Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors

Piro Lito, Anna Saborowski, Jingyin Yue et al. · Cancer Cell · 2014 · 304 citations · Full text

Effective Mek Inhibition, Kras Mutant Tumors, Signaling Pathway +9

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

Johannes Zuber, Katherine McJunkin, Christof Fellmann et al. · Nature Biotechnology · 2010 · 273 citations

Functional Genomics, Natural Sciences, Rna Biology +7

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay

Christof Fellmann, Johannes Zuber, Katherine McJunkin et al. · Molecular Cell · 2011 · 228 citations · Full text

Rna Processing, Systems Biology, Functional Genomics +13