K. Jeff Thrasher

Discovery and Synthesis of [6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]- 2-(4-hydroxyphenyl)]benzo[<i>b</i>]thiophene:  A Novel, Highly Potent, Selective Estrogen Receptor Modulator

Alan D. Palkowitz, Andrew L. Glasebrook, K. Jeff Thrasher et al. · Journal of Medicinal Chemistry · 1997 · 177 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

Quinazolinone cholecystokinin-B receptor ligands

Melvin J. Yu, K. Jeff Thrasher, Jefferson R. McCowan et al. · Journal of Medicinal Chemistry · 1991 · 63 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Dibasic Benzo[<i>b</i>]thiophene Derivatives as a Novel Class of Active Site-Directed Thrombin Inhibitors. 1. Determination of the Serine Protease Selectivity, Structure−Activity Relationships, and Binding Orientation

Daniel J. Sall, Jolie Bastian, John A. Buben et al. · Journal of Medicinal Chemistry · 1997 · 54 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Phenothiazines as lipid peroxidation inhibitors and cytoprotective agents

Melvin J. Yu, Jefferson R. McCowan, K. Jeff Thrasher et al. · Journal of Medicinal Chemistry · 1992 · 45 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Discovery of <i>N</i>-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3<i>R</i>)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model

Kevin R. Fales, F. George Njoroge, Harold B. Brooks et al. · Journal of Medicinal Chemistry · 2017 · 33 citations · Full text

Medicine, Oncology, Pharmacology +14