Melvin J. Yu

In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B.

Murray J. Towle, Kathleen A. Salvato, John Budrow et al. · PubMed · 2001 · 491 citations

Medicine, Medicinal Chemistry, Oncology +15

Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389

Galina Kuznetsov, Murray J. Towle, Hongsheng Cheng et al. · Cancer Research · 2004 · 267 citations

Medicine, Oncology, Pharmacology +17

Eribulin Induces Irreversible Mitotic Blockade: Implications of Cell-Based Pharmacodynamics for <i>In vivo</i> Efficacy under Intermittent Dosing Conditions

Murray J. Towle, Kathleen A. Salvato, Bruce F. Wels et al. · Cancer Research · 2010 · 142 citations

Medicine, Oncology, Pharmacology +16

Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo

Marc S. Lamphier, Wanjun Zheng, Eicke Latz et al. · Molecular Pharmacology · 2013 · 141 citations

Life Sciences, Immunology, Pharmacology +17

Structurally simplified macrolactone analogues of halichondrin B

Boris M. Seletsky, Yuan Wang, Lynn D. Hawkins et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 71 citations

Pharmacy, Chemistry, Medicinal Chemistry +12