Melvin M. Evers

AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington’s Disease Minipig Model

Melvin M. Evers, Jana Miniarikova, Štefan Juhás et al. · Molecular Therapy · 2018 · 157 citations · Full text

AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington’s disease

Jana Miniarikova, Virginie Zimmer, Raygene Martier et al. · Gene Therapy · 2017 · 100 citations · Full text

Genetics, Rat Model, Mutant Huntingtin Aggregation +18

Targeting Several CAG Expansion Diseases by a Single Antisense Oligonucleotide

Melvin M. Evers, Barry A. Pepers, J.C.T. van Deutekom et al. · PLoS ONE · 2011 · 98 citations · Full text

AAV5-miHTT Gene Therapy Demonstrates Sustained Huntingtin Lowering and Functional Improvement in Huntington Disease Mouse Models

Elisabeth A Spronck, Cynthia Brouwers, Astrid Vallès et al. · Molecular Therapy — Methods & Clinical Development · 2019 · 85 citations · Full text

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Lodewijk J.A. Toonen, Maurice Overzier, Melvin M. Evers et al. · Molecular Neurodegeneration · 2018 · 75 citations · Full text