Concepedia

Cynthia Brouwers

CB

Statistics

Publications

8

Citations

608

H-Index

8

Active since

2017

Affiliations

UniQure (Netherlands)(Current)

Leiden University Medical Center

University of British Columbia

BC Children's Hospital

IRBM Science Park

Cynthia Brouwers is an author at UniQure (Netherlands) specializing in neurodegenerative disorders, gene therapy, and life sciences.

ORCID

Publications per year

2017–2022

8

Publications

8

AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington’s Disease Minipig Model

Melvin M. Evers, Jana Miniarikova, Štefan Juhás et al. · Molecular Therapy · 2018 · 162 citations · Full text

, , +17

AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington’s disease

Jana Miniarikova, Virginie Zimmer, Raygene Martier et al. · Gene Therapy · 2017 · 105 citations · Full text

, , +17

AAV5-miHTT Gene Therapy Demonstrates Sustained Huntingtin Lowering and Functional Improvement in Huntington Disease Mouse Models

Elisabeth A. Spronck, Cynthia Brouwers, Astrid Vallès et al. · Molecular Therapy — Methods & Clinical Development · 2019 · 88 citations · Full text

, , +17

Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease

Nicholas S. Caron, Amber L. Southwell, Cynthia Brouwers et al. · Nucleic Acids Research · 2019 · 73 citations · Full text

, , +17

AAV5-miHTT Lowers Huntingtin mRNA and Protein without Off-Target Effects in Patient-Derived Neuronal Cultures and Astrocytes

Sonay Keskin, Cynthia Brouwers, Marina Sogorb-González et al. · Molecular Therapy — Methods & Clinical Development · 2019 · 70 citations · Full text

, , +17

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