Concepedia

AAV5-miHTT Gene Therapy Demonstrates Sustained Huntingtin Lowering and Functional Improvement in Huntington Disease Mouse Models

Elisabeth A Spronck, Cynthia Brouwers, Astrid Vallès, Martin de Haan, Harald Petry, S J van Deventer, Pavlina Konstantinova, Melvin M. Evers

Molecular Therapy — Methods & Clinical Development · 2019 · 85 citations · 26 references

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References

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A new mathematical model for relative quantification in real-time RT-PCR

Michael W. Pfaffl · Nucleic Acids Research · 2001 · 34.3K citations · Full text

Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home

Jamie Adams, Karthik Dinesh, Mulin Xiong et al. · Digital Biomarkers · 2017 · 3.2K citations · Full text

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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Huntington's disease: from molecular pathogenesis to clinical treatment

Christopher A. Ross, Sarah J. Tabrizi · The Lancet Neurology · 2010 · 1.7K citations

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Nuclear and Neuropil Aggregates in Huntington’s Disease: Relationship to Neuropathology

Claire‐Anne Gutekunst, Shihua Li, Hong Yi et al. · Journal of Neuroscience · 1999 · 902 citations · Full text

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