David P. Carney

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Medicine, Medicinal Chemistry, Molecular Biology +14

SIRT1 Activation by Small Molecules

Han Dai, Lauren Kustigian, David P. Carney et al. · Journal of Biological Chemistry · 2010 · 213 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

J. Joshua Smith, Renée Deehan Kenney, David Gagné et al. · BMC Systems Biology · 2009 · 211 citations · Full text

Life Sciences, Molecular Biology, Systems Biology +17

Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3

Lei Jin, Heidi L. Galonek, Kristine Israelian et al. · Protein Science · 2009 · 150 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Discovery of Imidazo[1,2- <i>b</i> ]thiazole Derivatives as Novel SIRT1 Activators

Chi B. Vu, Jean E. Bemis, Jeremy S. Disch et al. · Journal of Medicinal Chemistry · 2009 · 120 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9