Jean E. Bemis

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Diabetes Management, Medicine, Diabetes +9

A protein deacetylase SIRT1 is a negative regulator of metalloproteinase‐9

Yuji Nakamaru, Chaitanya Vuppusetty, Hiroo Wada et al. · The FASEB Journal · 2009 · 223 citations

Inflammatory Lung Disease, Advanced Lung Disease, Lung Inflammation +18

Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes

Lei Jin, Wentao Wei, Yaobin Jiang et al. · Journal of Biological Chemistry · 2009 · 204 citations · Full text

Protein Chemistry, Aldo-keto Reductase, Biochemistry +13

Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3

Lei Jin, Heidi L. Galonek, Kristine Israelian et al. · Protein Science · 2009 · 147 citations · Full text

Discovery of Imidazo[1,2- <i>b</i> ]thiazole Derivatives as Novel SIRT1 Activators

Chi B. Vu, Jean E. Bemis, Jeremy S. Disch et al. · Journal of Medicinal Chemistry · 2009 · 117 citations · Full text