David Gagné

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Medicine, Medicinal Chemistry, Molecular Biology +14

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

J. Joshua Smith, Renée Deehan Kenney, David Gagné et al. · BMC Systems Biology · 2009 · 211 citations · Full text

Life Sciences, Molecular Biology, Systems Biology +17

Collagen VI is a basement membrane component that regulates epithelial cell–fibronectin interactions

Jean‐François Groulx, David Gagné, Yannick D. Benoit et al. · Matrix Biology · 2011 · 129 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Discovery of Imidazo[1,2- <i>b</i> ]thiazole Derivatives as Novel SIRT1 Activators

Chi B. Vu, Jean E. Bemis, Jeremy S. Disch et al. · Journal of Medicinal Chemistry · 2009 · 120 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Integrin‐linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin‐dependent mechanism

David Gagné, Jean‐François Groulx, Yannick D. Benoit et al. · Journal of Cellular Physiology · 2009 · 75 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16