Ryuichi Okamoto

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell

Shiro Yui, Tetsuya Nakamura, Toshiro Sato et al. · Nature Medicine · 2012 · 782 citations

Regenerative Medicine, Functional Engraftment, Developmental Biology +9

Damaged epithelia regenerated by bone marrow–derived cells in the human gastrointestinal tract

Ryuichi Okamoto, Tomoharu Yajima, Motomi Yamazaki et al. · Nature Medicine · 2002 · 386 citations

Regenerative Medicine, Developmental Biology, Mucosal Immunology +9

Macrophage-derived IL-18–mediated intestinal inflammation in the murine model of Crohn's disease

Takanori Kanai∥, Mamoru Watanabe, Akira Okazawa et al. · Gastroenterology · 2001 · 202 citations

Inflammation, Chronic Inflammatory Diseases, Cytokine +13

Requirement of Notch activation during regeneration of the intestinal epithelia

Ryuichi Okamoto, Kiichiro Tsuchiya, Yasuhiro Nemoto et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2008 · 177 citations

Regeneration, Chronic Inflammatory Diseases, Immunology +24

Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis

Michio Onizawa, Takashi Nagaishi, Takanori Kanai∥ et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2009 · 162 citations

Inflammation, Mucosal Immunology, Immune Regulation +15