Michio Onizawa

The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis

Michio Onizawa, Shigeru Oshima, Ulf Schulze‐Topphoff et al. · Nature Immunology · 2015 · 273 citations · Full text

Ubiquitin-modifying Enzyme A20, Kinase Ripk3, Signal Transduction +10

A20 Restricts Ubiquitination of Pro-Interleukin-1β Protein Complexes and Suppresses NLRP3 Inflammasome Activity

Bao Duong, Michio Onizawa, Juan A. Osés-Prieto et al. · Immunity · 2015 · 264 citations · Full text

Inflammation, Cytokine, Inflammatory Disease +14

Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210

Haopeng Wang, Henrik Flach, Michio Onizawa et al. · Nature Immunology · 2014 · 250 citations · Full text

Hypoxia-regulated Microrna Mir-210, Medicine, Natural Sciences +10

Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme

Timothy T. Lu, Michio Onizawa, Gianna Hammer et al. · Immunity · 2013 · 210 citations · Full text

Complex Deubiquitinating Enzyme, Protein Function, Biochemistry +5

Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis

Michio Onizawa, Takashi Nagaishi, Takanori Kanai∥ et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2009 · 162 citations

Inflammation, Mucosal Immunology, Immune Regulation +15