Damaged epithelia regenerated by bone marrow–derived cells in the human gastrointestinal tract

Ryuichi Okamoto, Tomoharu Yajima, Motomi Yamazaki, +7

Nature Medicine

Regenerative MedicineDevelopmental BiologyMucosal ImmunologyMedicineHuman Gastrointestinal Tract +7

Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes.

Masahiko Watanabe, Yoshitaka Ueno, Tomoharu Yajima, +6

Journal of Clinical Investigation

ImmunologyImmune RegulationPathologyGastroenterologyImmunologic Mechanism +15

Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease

Hiromasa Takaishi, Takahiro Matsuki, Atsushi Nakazawa, +13

International Journal of Medical Microbiology

InflammationIntestinal Microflora ConstitutionDysbiosisAutoimmune DiseaseMucosal Immunology +10

Interleukin 7 Transgenic Mice Develop Chronic Colitis with Decreased Interleukin 7 Protein Accumulation in the Colonic Mucosa

Mamoru Watanabe, Yoshitaka Ueno, Tomoharu Yajima, +11

The Journal of Experimental Medicine

Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients

Katsuyoshi Matsuoka, Yasushi Iwao, Takeshi Mori, +11

The American Journal of Gastroenterology

Novel, Objective, Multivariate Biomarkers Composed of Plasma Amino Acid Profiles for the Diagnosis and Assessment of Inflammatory Bowel Disease

Tadakazu Hisamatsu, Susumu Okamoto, Masaki Hashimoto, +16

PLoS ONE

Risk-adapted pre-emptive therapy for cytomegalovirus disease in patients undergoing allogeneic bone marrow transplantation

Takehiko Mori, Shinichiro Okamoto, Satoshi Matsuoka, +8

Bone Marrow Transplantation

Cell TherapyTransplantationCytomegalovirus DiseaseImmunologyRisk-adapted Pre-emptive Therapy +8

Clinical significance of cytomegalovirus (CMV) antigenemia in the prediction and diagnosis of CMV gastrointestinal disease after allogeneic hematopoietic stem cell transplantation

Takehiko Mori, Shunsuke Mori, Yoshinobu Kanda, +10

Bone Marrow Transplantation

TransplantationIntestinal TransplantationCmv Gastrointestinal DiseaseStem Cell TransplantationHematology +9

Mucosal T Cells Expressing High Levels of IL-7 Receptor Are Potential Targets for Treatment of Chronic Colitis

Motomi Yamazaki, Tomoharu Yajima, M. Tanabe, +11

The Journal of Immunology

Increase of Bone Marrow–Derived Secretory Lineage Epithelial Cells During Regeneration in the Human Intestine

Tomoko Matsumoto, Ryuichi Okamoto, Tomoharu Yajima, +13

Gastroenterology

Regenerative MedicineImmune Cell DevelopmentMedicineImmunologyStem Cell Research +6