P. Dan Cook

Evaluation of 2‘-modified oligonucleotides containing 2‘-deoxy gaps as antisense inhibitors of gene expression

Brett P. Monia, Elena A. Lesnik, C. Gonzalez et al. · Journal of Biological Chemistry · 1993 · 770 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +16

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Andrew M. Kawasaki, Martin D. Casper, Susan M. Freier et al. · Journal of Medicinal Chemistry · 1993 · 436 citations

Life Sciences, Molecular Biology, Bioorthogonal Chemistry +16

Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

Lendell L. Cummins, Stephen R. Owens, Lisa M. Risen et al. · Nucleic Acids Research · 1995 · 361 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure−Activity Relationships of Novel 2-Substituted Quinazoline Antibacterial Agents

Pei‐Pei Kung, Martin D. Casper, Kimberley L. Cook et al. · Journal of Medicinal Chemistry · 1999 · 226 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Elena A. Lesnik, Charles J. Guinosso, Andrew M. Kawasaki et al. · Biochemistry · 1993 · 202 citations

Pharmacy, Biochemistry, Molecular Biology +17