Stephen R. Owens

Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

Lendell L. Cummins, Stephen R. Owens, Lisa M. Risen et al. · Nucleic Acids Research · 1995 · 361 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Characterization of a Potent and Specific Class of Antisense Oligonucleotide Inhibitor of Human Protein Kinase C-α Expression

Robert A. McKay, Loren Miraglia, Lendell L. Cummins et al. · Journal of Biological Chemistry · 1999 · 226 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14

On-Line HPLC Electrospray Mass Spectrometry of Phosphorothioate Oligonucleotide Metabolites

Hans Gaus, Stephen R. Owens, Michael Winniman et al. · Analytical Chemistry · 1997 · 114 citations

Life Sciences, Biochemistry, Drug Metabolism +16

Zwitterionic oligonucleotides with 2′-O-[3-(N,N-dimethylamino)propyl]-RNA modification: synthesis and properties

Thazha P. Prakash, Muthiah Manoharan, Allister S. Fraser et al. · Tetrahedron Letters · 2000 · 43 citations

Pharmacy, Biotechnology, Molecular Biology +12