Allister S. Fraser

Solution Phase Combinatorial Chemistry. Discovery of Novel Polyazapyridinophanes with Potent Antibacterial Activity by a Solution Phase Simultaneous Addition of Functionalities Approach

Haoyun An, Lendell L. Cummins, Richard H. Griffey et al. · Journal of the American Chemical Society · 1997 · 73 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Zwitterionic oligonucleotides with 2′-O-[3-(N,N-dimethylamino)propyl]-RNA modification: synthesis and properties

Thazha P. Prakash, Muthiah Manoharan, Allister S. Fraser et al. · Tetrahedron Letters · 2000 · 43 citations

Pharmacy, Biotechnology, Molecular Biology +12

2‘-<i>O</i>-[2-(Methylthio)ethyl]-Modified Oligonucleotide:  An Analogue of 2‘-<i>O</i>-[2-(Methoxy)-ethyl]-Modified Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA

Thazha P. Prakash, Muthiah Manoharan, Andrew M. Kawasaki et al. · Biochemistry · 2002 · 34 citations

Life Sciences, Biochemistry, Molecular Biology +17

Synthesis and conformational properties of 2′‐deoxy‐2′‐methylthio‐pyrimidine and ‐purine nucleosides: Potential antisense applications

Allister S. Fraser, Patrick Wheeler, P. Dan Cook et al. · Journal of Heterocyclic Chemistry · 1993 · 27 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Solution Phase Combinatorial Chemistry. Synthesis of Novel Linear Pyridinopolyamine Libraries with Potent Antibacterial Activity

Haoyun An, Becky D. Haly, Allister S. Fraser et al. · The Journal of Organic Chemistry · 1997 · 25 citations

Pharmacy, Medicinal Chemistry, Combinatorial Chemistry +12