Lendell L. Cummins

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Andrew M. Kawasaki, Martin D. Casper, Susan M. Freier et al. · Journal of Medicinal Chemistry · 1993 · 436 citations

Life Sciences, Molecular Biology, Bioorthogonal Chemistry +16

Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

Lendell L. Cummins, Stephen R. Owens, Lisa M. Risen et al. · Nucleic Acids Research · 1995 · 361 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Pharmacokinetic properties of several novel oligonucleotide analogs in mice.

Stanley T. Crooke, Melissa Graham, J E Zuckerman et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 228 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Characterization of a Potent and Specific Class of Antisense Oligonucleotide Inhibitor of Human Protein Kinase C-α Expression

Robert A. McKay, Loren Miraglia, Lendell L. Cummins et al. · Journal of Biological Chemistry · 1999 · 226 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Elena A. Lesnik, Charles J. Guinosso, Andrew M. Kawasaki et al. · Biochemistry · 1993 · 202 citations

Pharmacy, Biochemistry, Molecular Biology +17